ORALHERP : treatment for labial herpes

Overview

ORALHERP is a filmogen liquid bandage specifically designed for the treatment of labial herpes lesions. This product targets pro-inflammatory proteins, contaminants, and impurities, providing a comprehensive approach to lesion treatment.

Mode of action

ORALHERP operates in three stages to aid in the healing of labial herpes lesions:

Protective Barrier Effect:

The product forms a protective barrier over the lesion, preventing the worsening of the lesion and the spread of the virus. 

Osmotic and Cleaning Effect:

ORALHERP aids in cleaning the lesion by removing impurities and contaminants, providing a clean environment for healing.

Cellular Repair and Growth Effect:

The product promotes the repair and growth of cells in the affected area, accelerating the healing process.

Clinical Trial

A single arm, prospective, multi-centric clinical trial. 

Key Findings

Participants: The clinical trial involved 60 patients with visible lesions of herpes labialis.

Treatment: The test product, Hp-OR, was applied topically on the lesion 3-4 times per day for up to 14 consecutive days.

Virus Reduction:

• A 38% reduction in the amount of free virus particles was observed 2 hours after the first application.
• The reduction was 52% after 4 days, 70% after 7 days, and 100% after 14 days.

Lesion Size:

• The mean size of the lesions reduced from 1.528 cm² on day 1 to 0.683 cm² on day 4 (a 55.3% reduction).
• The lesion size further reduced to 0.193 cm² by day 7 (an 87.4% reduction), and the lesions were completely healed by day 14.

Symptom Relief:

• Significant reduction in symptoms such as itching, burning, and pain was noted. The majority of patients reported improvement in these symptoms within the first 4 days.
• No signs of itching, burning, or pain were reported by any of the patients by the end of the study.

Safety:

• No undesirable topical effects were reported by the patients, indicating that the product is safe for topical application on labial herpes lesions.
• Standard blood biochemical and urine parameters showed no significant changes before and after the treatment, further confirming the safety of the product.

Conclusion: The study concluded that neutralizing and eliminating the free virus particles from the open lesion is one of the best strategies to treat labial herpes .

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